Nebraska is looking to defensive end Zach Potter to spur improvement in defense after the Blackshirts struggled last week against Missouri.
Oklahoma State's offense ranks second in the Big 12 with more than 234 rushing yards per game.
Potter leads the team in both tackles for a loss and sacks. The 6-7, 285-pound junior from Omaha was called to fill in for Adam Carriker, who is in his rookie season with the St. Louis Rams.
The Cornhuskers worked out in shoulder pads and shorts Thursday and return to the field for a walkthrough Friday at Memorial Stadium.
Kickoff for the Saturday matchup is at 11:37 a.m., and the game can be seen on a Fox Sports Net pay-per-view.